When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

The universal features that define genomic regions acting as replication origins remain unclear. In this study, we mapped a set of origins in Trypanosoma brucei using stranded short nascent strand ...

Researchers discovered that stiff DNA segments inside nucleosomes physically block chromatin remodeling. The remodeling ...

Within the nucleus of every cell are long strings of DNA, the code that holds all the information needed to make and control every cell within a living organism. DNA, which stands for deoxyribonucleic ...

Bioscientists have uncovered a tiny detail that could help us understand how DNA replicates with such astounding accuracy. When cells reproduce, the internal mechanisms that copy DNA get it right ...

On 22 May 2019, scientists from Queen's University boarded a modified Falcon 20 aircraft at Ottawa airport. Scheduled was a ‘vomit comet’ flight, where the plane repeatedly climbs to 8km in a steep ...

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...