New hifiasm-ONT assembly method delivers high-quality, cost-efficient near T2T assemblies using standard Oxford Nanopore Simplex reads, broadening access to comprehensive genome assemblies across ...

We consider the specialization of the primal simplex algorithm to the problem of finding a tree of directed shortest paths from a given node to all other nodes in a network of n nodes or finding a ...

While sitting in a courtroom, waiting to find out if he would be chosen for jury duty, Daniel Spielman had a revelation-all the work he and colleague Shanghua Teng had built up over the past three ...

The death of mathematician George Dantzig is a scientific watershed. Dantzig developed "linear programming" and the simplex method, used to solve complex efficiency problems for large organizations.

These criteria are useful when you want to divide a time-consuming optimization problem into a series of smaller problems. Since the Nelder-Mead simplex algorithm does not use derivatives, no ...

This is a preview. Log in through your library . Abstract We devise a new simplex pivot rule which has interesting theoretical properties. Beginning with a basic feasible solution, and any nonbasic ...

OXFORD, England--(BUSINESS WIRE)--A new paper, released this week on bioRxiv, introduces hifiasm-ONT, a breakthrough genome assembly algorithm that enables partially phased, near telomere-to-telomere ...